Projects with 30,000 Patients

The goal of the LOOP Zurich is to improve the understanding of diseases, thereby facilitating the development of innovative, causal therapies. With this aim, teams of scientific experts at the partner institutions will join forces to work in the fields of biomedical research, bioinformatics, and clinical research.

1. Biomedical research: Funded projects will investigate specific human diseases, using mathematical models to do quantitative analysis of patient data as a basis for new hypotheses. This research will involve teams of specialists in genomics, proteomics, metabolomics, and high-content imaging.
2. Bioinformatics: Data analysis and data modeling based on available patient, clinical, and health data are key tools used at The LOOP Zurich. New computational approaches will emerge, and tissue phenotypes will be spatially analyzed to better understand the mechanisms of diseases.
3. Clinical research: Physicians, clinical researchers, and scientists at The LOOP Zurich will be investigating disease that are treatable but not curable. In collaboration with scientists and biocomputer scientists, they will carry out phenotypic disease analyses and develop new methods for diagnosis and treatment.

The LOOP Zurich’s work revolves around the use of big data to the benefit of the individual patient. Using data is crucial to generate benefits for patients and enhance the provision of healthcare.

The aim of projects run within the framework of The LOOP Zurich is to translate results from the lab into patient treatment, and back. Findings gathered in preclinical trials will be efficiently transferred to subsequent clinical trials. This process is facilitated by the clinical research expertise available in hospitals and clinical study centers, which is an important factor in successful translation.